Rocuronium EP Impurity H

Rocuronium EP Impurity H - Names and Identifiers

Name	1,2-Dehydro-3-oxo RocuroniuM BroMide
Synonyms	Rocuronium impurity H Rocuronium EP Impurity H 1-((5S,8R,9S,10S,13S,14S,16S,17R) 1,2-Dehydro-3-oxo RocuroniuM BroMide Rocuronium Bromide EP Impurity H Bromide RocuroniuM BroMide IMpurity 21 (EP iMpurity H) 1-((5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-10,13-dimethyl-2-morpholino-3-oxo-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium
CAS	1190105-67-9

Rocuronium EP Impurity H - Physico-chemical Properties

Molecular Formula	C32H49BrN2O4
Molar Mass	605.64646
Melting Point	155 - 160°C
Solubility	Chloroform (Slightly, Sonicated), Methanol (Slightly)
Appearance	Solid
Color	White to Dark Yellow
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic

Rocuronium EP Impurity H - Introduction

1,2-dehydro-3-oxo RocuroniuM BroMide is an organic compound with the chemical formula C4H4BrNO2. Its appearance is white crystal or crystalline powder.

1,2-dehydro-3-oxo RocuroniuM BroMide is commonly used as an intermediate in the field of medicine, mainly for the synthesis of drugs. It can be used in the preparation of antibiotics, analgesics and sedatives, etc. In addition, 1,2-dehydro-3-oxo RocuroniuM BroMide can also be used as an intermediate in the preparation of veterinary drugs, pesticides and dyes.

1,2-dehydro-3-oxo RocuroniuM BroMide has two main preparation methods. One is through the reaction of benzoic acid and tetrahydrofuran, through the bromination reaction to obtain RocuroniuM BroMide, and then through the reduction reaction to obtain 1,2-dehydro-3-oxo RocuroniuM BroMide. The other is through the reaction of p-chlorobenzoic acid and phosphorus oxychloride, through bromination reaction to obtain RocuroniuM BroMide, and then through reduction reaction to obtain 1,2-dehydro-3-oxo RocuroniuM BroMide.

For the safety information of 1,2-dehydro-3-oxo RocuroniuM BroMide, it is an organic compound with certain toxicity. During use, care should be taken to avoid direct contact with skin and eyes to avoid irritation and damage. Good ventilation should be provided and appropriate protective equipment such as gloves and goggles should be worn. During storage and transportation, avoid contact with fire and oxidant to prevent fire or explosion. If accidentally inhaled or ingested, should immediately seek medical treatment.

Last Update：2024-04-09 20:52:54